RAMS（ラマン活性化マイクロフルイディックソーター）

Applications

· Soil Microbiome Analysis.
· Active Bacteria Identification in Seawater.
· Efficiently Mining of Microbial Resources.
· Rapid Antimicrobial Sensitivity Testing (AST) for Oral Microbiota.
· AST and Source Tracking of H. pylori in Gastric Mucosal Samples.
· Quality Inspection of Probiotic Products.

Key Features

• •Rapid, label-free profiling of metabolic phenotypes at single-cell resolution
• •Singe-cell Raman Spectra (SCRS) can readily distinguish microbial species and reveal catabolism, anabolism, metabolite-interaction network, stress/drug response, and interaction of cells simultaneously.
• •Single-cell DNA/RNA extraction and amplification with low bias and high genomic coverage
• •Cells isolated with RAMS are ideal for single-cell sequencing with reduced MDA amplification bias. The genome coverage of single E. coli cells can reach up to 99.5%, a significant increase over classical approaches (23%).
• •Precise and automated acquisition of target cells while maintaining biological activity
• •Maintain full visibility throughout the process. RAMS can precisely control the movement trajectory of target cells with optical tweezers, and encapsulate each cell into a microliter-scale microdroplet with minimal impact on biological activity.